Living with a food allergy can be overwhelming for both children and adults. Even trace amounts of foods such as peanuts, tree nuts, milk, egg, or sesame can cause allergic reactions. Oral Immunotherapy (OIT) is a specialized food allergy treatment that helps desensitize the immune system through gradually increasing doses of the allergenic food. OIT can reduce the risk of severe reactions from accidental exposure, improve quality of life, and help families manage food allergies with greater confidence.
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Allied Physicians Group is available for allergy care across New York and the greater metropolitan area.
Oral Immunotherapy (OIT) is an advanced food allergy treatment designed to help children and adults with IgE-mediated food allergies become less sensitive to the foods that trigger allergic reactions.
During OIT treatment, patients consume carefully measured and gradually increasing amounts of an allergenic food under the supervision of a trained allergy specialist. Over time, this process helps retrain the immune system to better tolerate the food, reducing the risk of severe reactions from accidental exposure.
OIT is not considered a cure for food allergies. However, many patients achieve a level of desensitization that provides increased protection and greater peace of mind in everyday life.
Food Allergies Treated with OIT
Oral Immunotherapy may be used to treat confirmed IgE-mediated allergies to one or more foods, including:
Peanut allergy
Tree nut allergies
Sesame allergy
Milk allergy
Egg allergy
Additional food allergies may be evaluated on an individual basis by your allergy specialist.
How Oral Immunotherapy Works
In a food allergy, the immune system mistakenly identifies a harmless food protein as a threat. Even a small amount of the food can trigger symptoms ranging from mild itching and hives to severe, life-threatening anaphylaxis.
OIT works by exposing the immune system to very small amounts of the allergenic food and gradually increasing the dose over time. With repeated exposure, the immune system becomes less reactive and more tolerant of the food.
This process, known as desensitization, can significantly reduce the risk of severe allergic reactions from accidental exposure.
You or your child may be a candidate for Oral Immunotherapy if you have a history of allergic reactions and testing confirms an IgE-mediated food allergy.
Candidates commonly include patients with allergies to:
Peanuts
Tree nuts
Sesame
Milk
Eggs
A comprehensive allergy evaluation, including skin testing and blood work, is required before treatment begins.
Every patient and family has unique goals. Treatment plans are personalized to help achieve the outcomes most important to you.
Common goals include:
Protection from Accidental Exposure
Many families choose OIT to reduce the risk of severe reactions caused by accidental ingestion of an allergenic food.
Expanded Diet Options
Some patients may eventually tolerate larger amounts of the food and enjoy greater dietary freedom.
Improved Quality of Life
Reducing anxiety surrounding food allergies can help children and families feel more confident at school, social events, restaurants, and while traveling.
Your allergy specialist will work closely with you throughout treatment to establish realistic goals and monitor progress.
The OIT Treatment Process
Before treatment begins, patients undergo:
Comprehensive allergy consultation
Skin prick testing
Blood testing
Review of medical history and treatment goals
The first OIT appointment typically lasts 2–4 hours. During this visit, the patient receives several carefully measured doses of the allergenic food while being closely monitored.
Patients return to the office regularly for supervised dose increases.
Up-dosing typically takes 6–11 months
Visits generally last about 1 hour
Patients continue daily dosing at home between appointments
Treatment often begins with a diluted liquid or powdered form of the allergenic food before progressing to the actual food itself.
Once the target dose is reached, patients continue daily maintenance dosing.
Maintenance typically lasts 2–5 years
Ongoing monitoring and follow-up visits are required
Repeat allergy testing is generally performed every 6–12 months
Benefits of Oral Immunotherapy
Many patients experience meaningful improvements in food allergy management, including:
Increased protection against accidental exposure
Reduced risk of severe allergic reactions
Greater confidence in daily activities
Improved quality of life for patients and families
Personalized treatment plans tailored to individual goals
Some patients may eventually maintain protection even after discontinuing daily therapy. Others may need ongoing exposure to maintain their desensitization.
Risks and Safety Information
Oral Immunotherapy is a medical treatment that carries risks and requires close supervision by an experienced allergy specialist.
Patients may experience:
Mouth or throat itching
Mild hives
Stomach discomfort
Nausea
Mild gastrointestinal symptoms
Reactions to treatment doses can occur.
Up to 10% of patients may experience anaphylaxis during treatment.
Emergency medications, including epinephrine, must be available at all times.
Approximately 1–5% of patients may develop Eosinophilic Esophagitis (EoE), an inflammatory condition affecting the esophagus.
Symptoms may include:
Difficulty swallowing
Food getting stuck
Heartburn
Chest discomfort
If EoE develops, treatment may need to be modified or discontinued.
Patients should:
Follow all dosing instructions exactly as prescribed
Carry epinephrine at all times
Complete all scheduled follow-up visits
Be supervised during home dosing
Doses should not be taken if the patient is experiencing:
Wheezing
Asthma symptoms
Fever
Vomiting
Diarrhea
Significant illness
Patients should also avoid strenuous exercise for:
1 hour before dosing
2 hours after dosing
Frequently Asked Questions About OIT
No. OIT is designed to desensitize the immune system and increase tolerance to an allergenic food. Most patients must continue regular exposure to maintain protection.
The up-dosing phase typically lasts 6–11 months. Maintenance dosing generally continues for 2–5 years.
Peanut, tree nut, sesame, milk, and egg allergies are commonly treated. Additional foods may be discussed during your consultation.
Missing a single dose typically does not require changes to treatment. Missing multiple doses may require dose adjustments. Patients should contact their allergy specialist for guidance before restarting treatment.
Office visits and supervised food allergy procedures are typically billed through insurance. Program fees may apply to cover additional services, education, materials, and support that are not reimbursed by insurance plans.
Yes. While OIT can significantly reduce the risk of reactions from accidental exposure, reactions can still occur during treatment. OIT does not guarantee complete protection.
The initial visit usually lasts 2–4 hours and involves several small doses of the allergenic food. Follow-up up-dosing visits generally last about 1 hour and include monitoring after the dose is administered.
Benefits of Allergy Care from Allied Physicians Group
The skilled allergy specialists at Allied Physicians Group provide the solutions needed to help patients safely navigate a trigger-filled world. We are dedicated to managing responses to food allergens through effective medicines, action plans, and more.
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